What type of hemodynamic change is commonly seen with hypercalcemia?

Hypercalcemia, which is an elevated level of calcium in the blood, can significantly affect cardiovascular function, leading to increased blood pressure. The underlying mechanism involves calcium's critical role in vascular smooth muscle contraction. High calcium levels can enhance contractility of the myocardium and cause vasoconstriction, resulting in an overall increase in systemic vascular resistance. As a consequence, there is an elevation in blood pressure.

Additionally, hypercalcemia is associated with increased cardiac output due to improved myocardial contractility, which further contributes to the rise in blood pressure. This combination of increased systemic vascular resistance and heightened cardiac output is what makes increased blood pressure a common hemodynamic change observed in patients with hypercalcemia. Understanding the relationship between calcium levels and vascular dynamics is essential for effective management in critical care settings.